OxiplexTS200™ monitors oxygen saturation and hemoglobin concentration in tissues.
The OxiplexTS200™ is the clinical version of the non-invasive, near infrared dual channel quantitative tissue oximeter that provides oxy- and deoxy-hemoglobin concentrations and oxygen saturation in the tissue on two separate and independent channels. Ergonomically designed for clinical use in the OR, ER and doctors office, the OxiplexTS200™ is the most versatile and advanced tissue oximeter in the market. A touchscreen monitor is integrated into the device making it portable and easy to use either as a patient bedside monitor or, using 10m long fibers, as an integral instrument of the OR room. The compact design includes easy access to calibrator, protected USB ports, pole mount clamp and a handle for easy transportation.
Notice: Investigational device. Limited by Federal (or United States) law to investigational use. The ISS OxiplexTS200™ is presently used for research only.
Applications of OxiplexTS200™
Several areas may benefit from the monitoring of the absolute values of tissue oxygenation, especially when pulse oximetry is not applicable because of the irregularity, or the lack of, the heartbeat, and in all the cases where the tissue oxygenation, and not the arterial oxygen saturation, is the parameter of interest. Therefore, the applications of the OxiplexTS200™ include but are not limited to:
Peripheral Vascular Disease
Monitoring Brain Oxygenation in OR/ER/ICU
- Anesthesiology
- Cardiothoracic & Vascular Surgery
- Neurosurgery
Attention Deficit Hyperactivity Disorder (ADHD)
Obstructive Sleep Apnea Syndrome
Women's Health and Obstetrics
Neonatal Applications
- Premature Infant Intensive Care
- Hemodynamic stress monitoring
Ergonomics
Sport Medicine and Kinesiology
- High altitude physiology
- Tissue Oxygenation in Hyperbaric Chambers
Specifications
Method of Operation | Frequency domain - multiple distance |
Modulation Frequency | 110 MHz |
Measurements |
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Light Sources |
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Light Detectors |
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Average Optical Power | Less than 1 mW |
Number of Measurement Channels | 2 |
Sensors |
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Spatial Resolution | 4 Emitter-Detector distances per sensor |
Data Acquisition Rate | From 20 ms to minutes |
Maximum Experiment Duration | Up to several days (250,000 points) |
Software Operating System | Windows 8 Embedded Standard |
Power Requirements | 110-240 Volt; 50/60 Hz |
Dimensions and Weight | 38 x 32 x 20 cm; 11 kg |
Sensors & Accessories
Adult Flexible Sensor
The flexible sensor is made from polyurethane rubber in which fiber optics and prisms are embedded. It has been designed for measurements on curved surfaces such as the head. Right hand and left hand versions are available for simultaneous dual head monitoring. The body is larger than the equivalent neonatal head scanner and is thus less susceptible to stray light and background light complications. The sensor may be held in place by medical adhesive that is attached to its surface.Key Features
- Low Profile, Very flexible and Comfortable
- Many choices concerning emitter distances and number of emitter positions
- Side entry fibers allow for maximum flexibility of the sensor
- Inline detector/emitter geometry maximizes overlap of sample tissue
- Allows measurements on curved surfaces
Key Characteristics
- Flexible rubber molded construction
- Four emitter positions with eight emitters
- Standard fiber length 2.5 m (up to 10 m fibers available)
- Standard emitter-detector distance; 2.0, 2.5, 3.0, 3.5 cm
- Custom emitter detector distances available:
1.5, 2.0, 2.5, 3.0 cm
2.5, 3.0, 3.5, 4.0 cm
Dual Flexible Sensor
The dual sensor optical probe, utilized for measurements on the forehead, has been developed for measurements that require the simultaneous data acquisition on both frontal lobes of the brain (for instance, sleep apnea, ADHD). The sensor is made of soft and flexible polyurethane and accounts for forehead curvature effects, as well as sampling through the skull into the brain (effective source-detector separation range). The sensor may be attached on the forehead by means of a medical adhesive in a symmetrical configuration, so each sensor acquires data simultaneously, from the right and the left frontal lobes of the brain respectively.Key Features
- Low Profile, Very flexible and Comfortable
- Many choices concerning emitter distances and number of emitter positions
- Side entry fibers allow for maximum flexibility of the scanner
- Inline detector/emitter geometry maximizes overlap of sample tissue
- Allows measurements on curved surfaces
Key Characteristics
- Flexible rubber molded construction
- Four emitter-detector distances
- Standard emitter-detector distance; 2.5, 3.0, 3.5, 4.0 cm
- Standard fiber length 2.5 m (up to 10 m fibers available)
Infant Flexible Sensor
The infant flexible sensor is made from polyurethane rubber in which the fiber optics and prisms are embedded. It has been designed for measurements on curved surfaces such as the head. Right hand and left hand versions are available for simultaneous dual head monitoring.Key Features
- Low Profile, Very flexible, Comfortable
- Side entry fibers allow for maximum flexibility of the scanner
- Inline detector/emitter geometry maximizes overlap of sample tissue
- Allows measurements on curved surfaces
Key Characteristics
- Flexible rubber molded construction
- Four emitter-detector positions with eight emitters
- Standard emitter-detector distance; 1.5, 2.0, 2.5, 3.0 cm
- Standard fiber length 2.5 m (up to 10 m fibers available)
- Minimum body size for neonatal applications
Rigid Sensor
The rigid sensor body is made from rugged plastic in which the eight fibers are protected and positioned. It has been optimized for measuring muscle properties at rest as well as during exercise. The body fits the contour of the hand for hand held measurements. Strap attachments allow for measurements during exercise.Key Features
- Rugged and versatile for general investigational use
- Optimal optical coupling efficiency which allows maximum signal
- Hand held or strapped on during exercise
- Maximum accuracy and precision for flat surfaces
Key Characteristics
- Rigid Plastic Body
- Standard fiber length 2.5 m (up to 10 m fibers available)
- Standard emitter detector distance; 2.0, 2.5, 3.0, 3.5 cm
- Integral Attachment Straps
- Custom emitter detector distances available:
1.5, 2.0, 2.5, 3.0 cm
2.5, 3.0, 3.5, 4.0 cm
3.0, 3.5, 4.0, 4.4 cm
MRI Compatible Sensors
MRI-compatible muscle sensor with optimized for use in a MRI, the fiber length is 10 m and the sensor contains no metal in the sensor body. The sensor body is made from rugged plastic.Key Features
- Rugged and versatile for general investigational use
- Optimal optical coupling efficiency which allows maximum signal
- Maximum accuracy and precision for flat surfaces
Key Characteristics
- Rigid Plastic Body
- Standard emitter-detector distance; 2.0, 2.5, 3.0, 3.5 cm
- Custom emitter detector distances available:
1.5, 2.0, 2.5, 3.0 cm
2.5, 3.0, 3.5, 4.0 cm
3.0, 3.5, 4.0, 4.4 cm
Accessories
Input Interface Module
The auxiliary input interface system is for data logging of up to four analog signals generated by external devices (pulse oximeter, blood pressure monitor, breathing rate monitor, inspired gas mixture monitor, etc). The data is sent to OxiplexTS or Imagent and is displayed along with oximetry measurements. This allows for the correlation of tissue oximetry data with a wide array of other measurements.Output Interface Module
The output system is for exporting OxiplexTS data to an external device. The signal can be output at 10 Hz or less, the OxiplexTS can make measurements up to 50 Hz. Four outputs, saturation and total hemoglobin concentration for both channels is provided.Click on a heading below to expand its contents.
Combined NIRS-DCS
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Cerebral Oxygen Metabolism in Neonates With Congenital Heart Disease Quantified by MRI and Optics. Jain, V., Buckley, E.M., Licht, D.J., Lynch, J.M., Schwab, P.J., Naim, M.Y., Lavin, N.A., Nicolson, S.C., Montenegro, L.M., Yodh, A.G., Wehrli, F.W. J Cereb Blood Flow Metab., 2014, 34(3), 380-8. |
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Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants. Lin, P.Y., Roche-Labarbe, N., Dehaes, M., Carp, S., Fenoglio, A., Barbieri, B., Hagan, K., Grant, P.E., Franceschini, M.A. J Vis Exp., 2013, (73), e4379. |
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Regional and Hemispheric Asymmetries of Cerebral Hemodynamic and Oxygen Metabolism in Newborns. Lin, P.Y., Roche-Labarbe, N., Dehaes, M., Fenoglio, A., Grant, P.E., Franceschini, M.A. Cereb Cortex., 2013, 23(2), 339-48. |
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Near-infrared Spectroscopy Assessment of Cerebral Oxygen Metabolism in the Developing Premature Brain. Roche-Labarbe, N., Fenoglio, A., Aggarwal, A., Dehaes, M., Carp, S.A., Franceschini, M.A., Grant, P.E. J Cereb Blood Flow Metab., 2012, 32(3), 481-8. |
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Optical Measurement of Cerebral Hemodynamics and Oxygen Metabolism in Neonates With Congenital Heart Defects. Durduran, T., Zhou, C., Buckley, E.M., Kim, M.N., Yu, G., Choe, R., Gaynor, J.W., Spray, T.L., Durning, S.M., Mason, S.E., Montenegro, L.M., Nicolson, S.C., Zimmerman, R.A., Putt, M.E., Wang, J., Greenberg, J.H., Detre, J.A., Yodh, A.G., Licht, D.J. J Biomed Opt., 2010, 15(3), 037004. |
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Noninvasive Optical Measures of CBV, StO(2), CBF Index, and rCMRO(2) in Human Premature Neonates' Brains in the First Six Weeks of Life. Roche-Labarbe, N., Carp, S.A., Surova, A., Patel, M., Boas, D.A., Grant, P.E., Franceschini, M.A. Hum Brain Mapp., 2010, 31(3), 341-52. |
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Increased Cerebral Blood Volume and Oxygen Consumption in Neonatal Brain Injury. Grant, P.E., Roche-Labarbe, N., Surova, A., Themelis, G., Selb, J., Warren, E.K., Krishnamoorthy, K.S., Boas, D.A., Franceschini, M.A. J Cereb Blood Flow Metab., 2009, 29(10), 1704-13. |
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Assessment of Infant Brain Development With Frequency-domain Near-infrared Spectroscopy. Franceschini, M.A., Thaker, S., Themelis, G., Krishnamoorthy, K.K., Bortfeld, H., Diamond, S.G., Boas, D.A., Arvin, K., Grant, P.E. Pediatr Res., 2007, 61(5 Pt 1), 546-51. |
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Developmental Changes of Optical Properties in Neonates Determined by Near-infrared Time-resolved Spectroscopy. Ijichi, S., Kusaka, T., Isobe, K., Okubo, K., Kawada, K., Namba, M., Okada, H., Nishida, T., Imai, T., Itoh, S. Pediatr Res., 2005, 58(3), 568-73. |
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In Vivo Cerebrovascular Measurement Combining Diffuse Near-infrared Absorption and Correlation Spectroscopies. Cheung, C., Culver, J.P., Takahashi, K., Greenberg, J.H., Yodh, A.G. Phys Med Biol., 2001, 46(8), 2053-65. |
Validation of NIRS-DCS
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Validation of Diffuse Correlation Spectroscopic Measurement of Cerebral Blood Flow Using Phase-encoded Velocity Mapping Magnetic Resonance Imaging. Buckley, E.M., Hance, D., Pawlowski, T., Lynch, J., Wilson, F.B., Mesquita, R.C., Durduran, T., Diaz, L.K., Putt, M.E., Licht, D.J., Fogel, M.A., Yodh, A.G. J Biomed Opt., 2012, 17(3), 037007. |
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Validation of Diffuse Correlation Spectroscopy Measurements of Rodent Cerebral Blood Flow With Simultaneous Arterial Spin Labeling MRI; Towards MRI-optical Continuous Cerebral Metabolic Monitoring. Carp, S.A., Dai, G.P., Boas, D.A., Franceschini, M.A., Kim, Y.R. Biomed Opt Express., 2010, 1(2), 553-565. |
DCS
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Diffuse Correlation Spectroscopy for Measurement of Cerebral Blood Flow: Future Prospects. Buckley, E.M., Parthasarathy, A.B., Grant, P.E., Yodh, A.G., Franceschini, M.A. Neurophotonics., 2014, 1(1), pii 011009. |
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Direct Measurement of Tissue Blood Flow and Metabolism With Diffuse Optics. Mesquita, R.C., Durduran, T., Yu, G., Buckley, E.M., Kim, M.N., Zhou, C., Choe, R., Sunar, U., Yodh, A.G. Philos Trans A Math Phys Eng Sci., 2011, 369(1955), 4390-406. |
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Influences of Tissue Absorption and Scattering on Diffuse Correlation Spectroscopy Blood Flow Measurements Irwin, D., Dong, L., Shang, Y., Cheng, R., Kudrimoti, M., Stevens, S.D., Yu, G. Biomed Opt Express., 2011, 2(7). |
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Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation Boas, D.A., Yodh, A.G. J. Opt. Soc. Am. A, 1997, 14(1), 192-215. |
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Scattering and Imaging with Diffusing Temporal Field Correlations Boas, D.A., Yodh, A.G. Physical Review Letters, 1995, 75(9), 1855-1859. |